COSMIC Mission

COSMIC delivers the next generation of systems medicine professionals who successfully combat complex human disorders. We will focus on B-cell lymphoma and rheumatoid arthritis, diseases that originate from abnormal functioning of the adaptive immune system, in particular the germinal center. COSMIC develops and integrates experimental and computational approaches, and establish a unique cross-fertilization between oncology and auto-immunity. 
Download: COSMIC Summary
  • COSMIC in numbers

    10 Beneficiaries
    7 Partner Organisations
    14 Early Stage Researchers (ESRs)
        -13 PhD students
        -1 Industrial researcher
    5 Companies
    9 European countries
        -NL, FR, SE, UK, IT, ES, DE, CH, EL
    5 Visiting Scientists
    4 External Trainers
    5 Members of External Advisory Board
    1 Ethics Advisor
  • COSMIC Research Background

    Systems Medicine

    One of the key question in systems biology is how biological systems (e.g., cells, molecular networks, germinal center) operate upon interaction with their external environment. Answering this question will generate knowledge about the dy­namics of complex systems and quantitative and explanatory computer models based on ex­perimental data.

    Systems medicine implements systems biology approaches in medical research and practice. This involves iterative and reciprocal feedback between clinical investigations and practice with computational, statistical and mathematical multiscale analysis and modelling of pathogenetic mechanisms, disease progression and remission, treatment responses, and adverse events as well as disease prevention at the individual patient level.

    Systems medicine aims at a measurable improvement of patient health through systems-based approaches and practice.

    Source: CASyM
    See also: EASyM
    Further reading: Schmitz, U., and Wolkenhauer, O. eds. (2016). Systems Medicine (New York: Springer)

    Adaptive immunity
    Germinal Center
    B-cell lymphoma
    Rheumatoid Arthritis
    Computational modelling
  • COSMIC Systems Medicine

    Through collaboration with existing systems medicine initiatives (e.g. EASyM, ISBE) COSMIC researchers contribute to systems medicine infrastructure and best practices that reduce time and costs to address clinical needs.

    At the same time this will promote Europe’s position in the health domain.
  • COSMIC Training

    An important aim of the Marie Sklodowska-Curie Action European Training Network (ETN) is to train young researchers (Early Stage Researchers, ESRs) with multi-disciplinary and multi-sectorial scientific and transferable skills required in systems medicine and translational medicine (WP2).

    COSMIC delivers 14 highly skilled systems medicine professionals who are able to address and solve complex clinical questions and to shape the next generation of systems medicine scientists.
Overview of the COSMIC e-learnig activities
ESR First Contact 
Organiser: B1a(AMC).
Setup: Video conference (WebEx). 4 hours in 2 weeks.
November 2018
Topic : The aim of this video conference is to allow the fellows to get to know their fellow colleagues at an early stage of the project. The video conference will be moderated by the COSMIC coordinators (Antoine van Kampen, Jeroen Guikema). The fellows provide a 10 minute powerpoint presentation about their (i) background (ii) previous research experience, (iii) individual COSMIC project, and (iv) hobbies. In addition, prior to the video conference the fellows will prepare 1 slide summary that will be used for outreach (e.g., COSMIC News, Facebook, Twitter). The coordinators will briefly introduce you to administrative (e.g., use of website, social media, PCDP) and training aspects (e-learning, workshops, local training) of COSMIC.
The landscape of translational medicine
Organiser: PO1 (ELH).
Duration: 2 weeks / 8hrs per week workload
November - December 2018

Topics: Translational medicine is a discipline in biomedical research that aims to turn observations in the laboratory, clinic and community into interventions that improve the health of individuals and the public. This training course introduces you to key aspects of translational research and medicines development. The course consists of five modules and each of these modules consists of different learning units. You will learn through lectures, videos, webcasts, tests and quizzes. You will start the online medical course with a general introduction to translational medicine. You will learn about the different research and development phases of a new medicine, including the challenges, risks and costs that are involved in the process. Hence you will learn about target validation and predictive models during modules 2 and 3. Learning module 4 will introduce you to Biomarkers and personalized medicine, so you will understand how to monitor drug effects in treated patients. During the last module 5 the focus will be on European regulations in this field.
More information:
Acknowledgements: This course is provided by EATRIS and was developed by the C-COMEND European training project (Erasmus plus programme)


 Elevate logo  Eatris logo  c commend logo


Essentials of on online course
Organiser: PO1 (ELH).
Duration: 5 weeks.
May - June 2019
Topics: Most fellows will have (future) teaching responsibilities. Broad introduction to the field of online learning, teach you how to communicate effectively and efficiently with students. Improve time management skills. fellows learn to select the most appropriate e-learning methods and use them optimally. Develop the abilities and experience required to teach effectively online.
Writing successful Grant Proposals
Organiser: PO1 (ELH).
Duration: 4 weeks.
Topics: Convey research ideas in a clear and compelling manner with realistic objectives, state-of-the-art methodology and a well-structured work plan and budget. Present yourself as the best person to carry out the research idea.
Project management
Organiser: PO1 (ELH).
Duration: 1 weeks.
Topics: Introduce fellows to the principles of effective project management and the application of these principles to their own projects. Planning, implementation and monitoring will be addressed. Personal and organisational context of research.
IPR and Patents
Organisers: ET3 (Sabina Heim).
Setup: online interactive training using video conferencing.
Duration: 1 day
Topics : What is IPR? What is a patent? Why should I apply for it? What can I use it for? What’s in it for me? What is the content of a patent? What is a patentable invention? What are the criteria for patentability? Balance between patenting and publication Overview of the patenting process Patenting and collaborating with Industry, etc.


29 April 2018 3360

EASyM conference

2nd Conference of the European Association of Systems Medicine (EASYM) This conference is…
27 January 2018 2968

Andien Vaes: new controller

New controller: Andien Vaes. Andien Vaes (AMR) takes over the tasks of Don van Velzen.…
23 December 2017 852

Biotecture becomes Science Matters

Biotecture becomes Science Matters Our Partner Organisation Biotecture changed their name…

COSMIC Highlights

29 September 2019 75

LINK - Extremadura en el Mundo

LINK - Extremadura en el Mundo Our fellow, Rodrigo Garcia Valiente took part as an…
22 February 2019 302

CERTH Highschool students

Highschool students at CERTH Rerun by popular demand. Bastien of PLANT.ID did so well…
11 February 2018 1866

COSMIC Coffee Mug

First COSMIC Merchandise During the kickoff meeting (8-9 February) all participants…


06 May 2018 764

5th European Congress of Immunology

5th European Congress of Immunology 2-5 september 2018 | Amsterdam RAI Exhibition and…
29 April 2018 1267

EASyM 2nd conference

2nd Conference of the European Association of Systems Medicine (EASYM) 7 - 9 November…
16 March 2018 2510

Workshop Applying bioinformatics and data science competency frameworks to ELIXIR Training

Workshop Applying bioinformatics and data science competency frameworks to ELIXIR…


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    Project coordination

    Prof. dr. A.H.C. van Kampen (Antoine)
    Bioinformatics Laboratory
    E: a.h.vankampen at
    P: +31 20 5667096

    Project management:
    Dr. Laurian Jongejan
    Department of Experimental Immunology
    E: l.zuidmeer at
    P: +31 20 5666819

    The Netherlands
    Academic Medical Center, University of Amsterdam

    Marie Skłodowska-Curie Actions

    The Marie Skłodowska-Curie actions (MSCA), named after the double Nobel Prize winning Polish-French scientist famed for her work on radioactivity, support researchers at all stages of their careers. One type of action is the European Training Network (ETN) aimed at joint research training by partners from academia, industry, and other organisation. ETNs facilitate the the researcher to experience different sectors and develop their transferable skills by working on joint research projects.


    COSMIC is a European Training Network funded from the European Union's Horizon 2020 research and innovation programme under grant agreement No 765158.

© 2018 COSMIC. All Rights Reserved.

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