COSMIC Mission

COSMIC delivers the next generation of systems medicine professionals who successfully combat complex human disorders. We will focus on B-cell lymphoma and rheumatoid arthritis, diseases that originate from abnormal functioning of the adaptive immune system, in particular the germinal center. COSMIC develops and integrates experimental and computational approaches, and establish a unique cross-fertilization between oncology and auto-immunity. 
 
Download: COSMIC Summary
 
  • COSMIC in numbers

    10 Beneficiaries
    7 Partner Organisations
    14 Early Stage Researchers (ESRs)
        -13 PhD students
        -1 Industrial researcher
    5 Companies
    9 European countries
        -NL, FR, SE, UK, IT, ES, DE, CH, EL
    5 Visiting Scientists
    4 External Trainers
    5 Members of External Advisory Board
    1 Ethics Advisor
  • COSMIC Research Background

    Systems Medicine

    One of the key question in systems biology is how biological systems (e.g., cells, molecular networks, germinal center) operate upon interaction with their external environment. Answering this question will generate knowledge about the dy­namics of complex systems and quantitative and explanatory computer models based on ex­perimental data.

    Systems medicine implements systems biology approaches in medical research and practice. This involves iterative and reciprocal feedback between clinical investigations and practice with computational, statistical and mathematical multiscale analysis and modelling of pathogenetic mechanisms, disease progression and remission, treatment responses, and adverse events as well as disease prevention at the individual patient level.

    Systems medicine aims at a measurable improvement of patient health through systems-based approaches and practice.

    Source: CASyM
    See also: EASyM
    Further reading: Schmitz, U., and Wolkenhauer, O. eds. (2016). Systems Medicine (New York: Springer)

    Adaptive immunity
    Germinal Center
    B-cell lymphoma
    Rheumatoid Arthritis
    Computational modelling
  • COSMIC Systems Medicine

    Through collaboration with existing systems medicine initiatives (e.g. EASyM, ISBE) COSMIC researchers contribute to systems medicine infrastructure and best practices that reduce time and costs to address clinical needs.

    At the same time this will promote Europe’s position in the health domain.
  • COSMIC Training

    An important aim of the Marie Sklodowska-Curie Action European Training Network (ETN) is to train young researchers (Early Stage Researchers, ESRs) with multi-disciplinary and multi-sectorial scientific and transferable skills required in systems medicine and translational medicine (WP2).

    COSMIC delivers 14 highly skilled systems medicine professionals who are able to address and solve complex clinical questions and to shape the next generation of systems medicine scientists.

 

Communication and public engagement

Outreach activities by the principal investigators and the research fellows ensures that COSMIC results are disseminated to society at large to raise awareness of research among the general public including patients, patient organisations, (secondary) school students, and teachers:

  • Talks at public meetings. COSMIC will stimulate research fellows to give presentations at public meetings. For example at TEDx;
  • Use of electronic media such as FacebookTwitter, and LinkedIn;
  • Patient Seminars are organised during which patients and medical doctors give a lecture about disease signs and symptoms as well as socio-economic consequences
  • EULAR/PARE will be invited to contribute to the training and Science Cafes. The European League Against Rheumatism (EULAR) is the organisation that represents the patients with arthritis/rheumatism, health professional and scientific societies of rheumatology of all the European nations.  PARE are the national organisations of People with Arthritis/Rheumatism in Europe.
  • Investing in the future: (secondary school) students and teachers. Research fellows make teaching material (e.g., presentation, computer lab) for secondary school students and their teachers. The fellows will use the teaching material at a local secondary school to enthuse students for systems medicine. Additionally, COSMIC results will also be included in university bachelor/master and company training programmes.
  • Best exposé written for lay public.  At the end of COSMIC during the 4th Annual Meeting, we will award a prize for the best systems medicine exposé written for lay public. Scientists from inside and outside COSMIC will be invited to participate. COSMIC will put effort into having this expose published through a wide range of channels that reach the general public (electronic and newspapers).

 

Highschool students at CERTH (February 2019)

Rerun by popular demand. Bastien of PLANT.ID did so well last time high school students visited the labs at the Center for Research and Technology Hellas (CERTH) that they decided to do it again! This time he teamed up with Laura Zaragoza Infante, an ESR of COSMIC and they shared their experiences of being part of a Marie Skłodowska-Curie Actions project. Got to love inter-ITN fraternization.

LauraCerth

LINK - Extremadura en el Mundo

COSMIC NEWS

29 April 2018 3359

EASyM conference

2nd Conference of the European Association of Systems Medicine (EASYM) This conference is…
27 January 2018 2968

Andien Vaes: new controller

New controller: Andien Vaes. Andien Vaes (AMR) takes over the tasks of Don van Velzen.…
23 December 2017 852

Biotecture becomes Science Matters

Biotecture becomes Science Matters Our Partner Organisation Biotecture changed their name…

COSMIC Highlights

29 September 2019 74

LINK - Extremadura en el Mundo

LINK - Extremadura en el Mundo Our fellow, Rodrigo Garcia Valiente took part as an…
22 February 2019 301

CERTH Highschool students

Highschool students at CERTH Rerun by popular demand. Bastien of PLANT.ID did so well…
11 February 2018 1865

COSMIC Coffee Mug

First COSMIC Merchandise During the kickoff meeting (8-9 February) all participants…

Events

06 May 2018 763

5th European Congress of Immunology

5th European Congress of Immunology 2-5 september 2018 | Amsterdam RAI Exhibition and…
29 April 2018 1267

EASyM 2nd conference

2nd Conference of the European Association of Systems Medicine (EASYM) 7 - 9 November…
16 March 2018 2510

Workshop Applying bioinformatics and data science competency frameworks to ELIXIR Training

Workshop Applying bioinformatics and data science competency frameworks to ELIXIR…

 

  • amc-small.jpg
    marie_curie_actions-small.png
    EU-flag-small.gif

    Project coordination

    Prof. dr. A.H.C. van Kampen (Antoine)
    Bioinformatics Laboratory
    E: a.h.vankampen at amc.uva.nl
    P: +31 20 5667096

    Project management:
    Dr. Laurian Jongejan
    Department of Experimental Immunology
    E: l.zuidmeer at amc.uva.nl
    P: +31 20 5666819

    The Netherlands
    Academic Medical Center, University of Amsterdam

    Marie Skłodowska-Curie Actions

    The Marie Skłodowska-Curie actions (MSCA), named after the double Nobel Prize winning Polish-French scientist famed for her work on radioactivity, support researchers at all stages of their careers. One type of action is the European Training Network (ETN) aimed at joint research training by partners from academia, industry, and other organisation. ETNs facilitate the the researcher to experience different sectors and develop their transferable skills by working on joint research projects.

    H2020

    COSMIC is a European Training Network funded from the European Union's Horizon 2020 research and innovation programme under grant agreement No 765158.









© 2018 COSMIC. All Rights Reserved.

Please publish modules in offcanvas position.